– Recent animal studies have shown a link between gut microbes and the health of the brain
– People with Alzheimer's disease have more gut inflammation, which may be the mechanism through which inflammation occur
– Higher gut inflammation is associated with higher levels of amyloid plaque accumulation in the brain, according to a new study
– Levels of calprotectin, a sign of inflammation, increased with levels of inflammation and memory test scores dropped
– Gut bacteria chemicals can stimulate inflammatory signals in our brains, and microbiome changes trigger gut changes that lead to system-wide inflammation
Increased gut permeability could result in higher blood levels of inflammatory molecules and toxins derived from gut lumen, leading to
systemic inflammation and potentially neural injury and neurodegeneration
– Researchers are testing mice to see if diet changes associated with increased inflammation can trigger the rodent version of Alzheimer's.